Primarily for students in departments other than biochemistry. Prerequisite: general and organic chemistry. An integration, from a dynamic point of view, of cellular constituents with the chemical processes of living systems: chemistry and function, mode of synthesis and degradation by the cell, the characterization and role of particular enzymes and coenzymes in these reactions, and the mechanisms of oxidation and energy production. Nucleic acids, replication, and the genetic code are also discussed. (Given at the Morningside campus.)

Prerequisites: a basic course in biochemistry or biology, or instructor�s permission.

Structure and organization of chromatin, nucleic acid hybridization, and sequence complexity of DNA, DNA and RNA sequencing methods, current views of replication and repair, transcription and translation, regulation of nucleic acid and protein syntheses, recombinant DNA techniques, gene transfer and gene duplication. Discussion of original papers and evaluation of experimental procedures and conclusions. Lectures preceded by an hour-long optional conference. (Given at the Morningside Campus.)